Trial Manager

Location: High Holborn, Central London

Salary: £36,000 – £42,000

Type of contract: Permanent

Hours: Full-time

Contract start: As soon as possible

The Intensive Care National Audit & Research Centre (ICNARC) is a small, independent, nationally and internationally respected, scientific, not-for-profit organisation (c40 staff in total), that uses accurate data to help improve the quality of critical care through audit, research and education, conducted with, and in the interests of, patients and those who care for them. Most recently, ICNARC has been centrally involved in the response to COVID-19 through daily/weekly reporting on admissions to, and outcomes from, intensive care and as the UK coordinating centre for the global platform trial, REMAP-CAP.

About the role

This is an exciting opportunity for a Trial Manager to bring experience in managing clinical trials to deliver research in a unique and challenging setting, and join an innovative and independent Clinical Trials Unit (UKCRC fully registered) to drive forward our adult critical care research portfolio. The successful candidates will be responsible for ensuring the effective coordination, start-up, on-going management and close-down of two NIHR funded studies:

  • UK-ROX (NIHR130508) is a large-scale, multi-centre, data-enabled, registry-embedded, randomised trial of a conservative oxygenation target of 90% (±2%) whilst receiving oxygen, versus usual care in critically ill adults. Funded under the NIHR’s commissioned call for ‘ambitious data-enabled trials’, UK-ROX will recruit 16,500 patients from 100 adult intensive care units in the UK. To ensure an efficient design, data collection is nested within the Case Mix Programme national clinical audit for adult intensive care (run by ICNARC) and will utilise additional routinely collected data from other national NHS sources.
  • Thresholds for Platelets (T4P, NIHR131822) is a randomised, comparative effectiveness trial which will aim to find the optimum threshold for platelet transfusion prior to invasive procedures in critically ill adults. T4P will randomly allocate 2550 critically ill patients, requiring an invasive procedure, to one of five transfusion thresholds below which they would receive a single dose of platelet transfusion delivered before or during the procedure and will compare the and will compare the clinical and cost effectiveness of each of these thresholds in order to identify the optimum.

The successful candidates will be expected to oversee the conduct, performance and delivery of the clinical trials and to supervise the staff working on them. They will be expected to ensure trials are delivered to high quality standards, regulatory requirements and meet trial objectives and deadlines.

What you will need to succeed

Applicants must have a degree in health services research, biomedical science (or allied subject), or equivalent experience, with experience and understanding of the principles of research methodology, and of successfully managing and co-ordinating previous trials in the NHS. They must have knowledge of the ethical and regulatory issues for research studies. They should have experience of supervising or managing junior colleagues within a team environment and have the ability to provide support and delegate effectively.

The successful candidate will need to have excellent interpersonal, team working and organisational skills together with a high level of attention to detail in all aspects of work.

The ability to relate to and communicate clearly, sensitively and effectively with people from a variety of professional and personal backgrounds are also essential.

What you’ll get in return

You will receive an annual salary in the range of £36-£42k.
You will also receive a benefits package including:

  • 25 days holiday per year;
  • flexible working;
  • interest-free season ticket loan;
  • enhanced pension scheme;
  • enhanced sick pay;
  • employee assistance programme;
  • access to a range of benefits and discounts focused on Health & Wellbeing, Family, Technology and Exercise & Fitness;
  • support with further academic/professional development.

How to apply

Please read the job description for the role. The person specification sets out the skills and experience we are looking for. Please use this link to submit a cover letter setting out your suitability for the role and a current CV.  Each document should be no longer than 2 sides of A4.

To access a PDF version of the job description please click here:
Trial Manager Job Description PDF

No agencies.

Interviews will be held on a rolling basis, and the advert will be closed early if an appointment is made prior to the closing date so please do not delay in applying.

“We are committed to equality of opportunity for all staff and applications from individuals are encouraged regardless of age, disability, sex, gender reassignment, sexual orientation, pregnancy and maternity, race, religion or belief and marriage and civil partnerships.”