Trial Manager x 2

Location:  High Holborn, Central London

Salary:  £36,000 – £42,000 (depending on experience) plus benefits

Type of contract:  1 x Permanent and 1 x Maternity cover (fixed term contract)

Hours:  Full-time

Contract start:  ASAP

Closing date:  1st July 2020 at noon

The Intensive Care National Audit & Research Centre (ICNARC) is a small, independent, nationally and internationally respected, scientific, not-for-profit organisation (c40 staff in total), using accurate data to help improve the quality of critical care through audit, research and education, conducted with, and in the interests of, patients and those who care for them. Most recently, ICNARC has been centrally involved in the response to COVID-19 through weekly reporting on admissions to, and outcomes from, intensive care and as the UK methods centre for the CMO endorsed REMAP-CAP trial which is currently recruiting in 120 centres in the UK.

About the role:

This is an exciting opportunity for 2 x Trial Managers to bring experience in managing clinical trials to deliver research in a unique and challenging setting, and join an innovative and independent Clinical Trials Unit (UKCRC fully registered) to drive forward our paediatric critical care research portfolio. The successful candidates will be responsible for ensuring the effective coordination, start-up, on-going management and close-down of three NIHR funded studies:

  • Oxy-PICU (NIHR 127547) is a randomised, multi centre, trial of conservative versus liberal oxygenation targets in critically ill children, investigating the clinical and cost effectiveness of using a conservative oxygen saturation target of 88-92% compared with a liberal oxygen saturation target of 95-100%. Oxy-PICU will recruit 2040 children from 15 UK paediatric intensive care units and is following on from the successful completion of the Oxy-PICU pilot study which completed in 2018 (Intensive Care Med 2018 Aug;44(8):1240-1248).
  • PRESSURE (NIHR128895) is a randomised, multi centre, trial evaluating the clinical and cost effectiveness of using a more permissive blood pressure target to guide careful titration of vasoactive drugs in critically ill children with hypotension. This study will recruit 1900 critically ill children from 17 UK paediatric intensive care units and will build on the success of the recently completed 65 Trial, which investigated the use of lower blood pressure targets in critically ill adults (JAMA 2020 Feb 12;323(10):938-49).
  • PICnIC (NIHR HTA 16/152/01) is a pilot cluster randomised clinical trial of the use of selective gut decontamination in critically ill children. This study will recruit 324 critically ill children from 6 UK paediatric intensive care units to assess feasibility of a definitive trial.

The successful candidates will be expected to oversee the conduct, performance and delivery of the clinical trials and to supervise the staff working on them. They will be expected to ensure trials are delivered to high quality standards, regulatory requirements and meet trial objectives and deadlines.

What you will need to succeed

Applicants must have a degree in health services research, biomedical science (or allied subject), or equivalent experience, with experience and understanding of the principles of research methodology, and of successfully managing and co-ordinating previous trials in the NHS. They must have knowledge of the ethical and regulatory issues for research studies. They should have experience of supervising or managing junior colleagues within a team environment and have the ability to provide support and delegate effectively.

The successful candidate will need to have excellent interpersonal, team working and organisational skills together with a high level of attention to detail in all aspects of work.

The ability to relate to and communicate clearly, sensitively and effectively with people from a variety of professional and personal backgrounds are also essential.

What you’ll get in return

In return you will receive an annual salary of £36,000 – £42,000 per annum working for a well-established, scientific organisation in the centre of London. You will also receive a generous benefits package including:

•           25 days holiday, plus Bank Holidays, per year and the opportunity to buy and sell annual leave;
•           flexible working which is fully embedded in our culture;
•           interest-free season ticket loans;
•           support with further academic/professional development; and
•           an enhanced pension contribution after your first year of employment.

Download Job description and Person Specification – Trial Manager (PDF).

How to apply

Please read the job description for the role. The person specification sets out the skills and experience we are looking for.

To apply for the role, please email your CV, cover letter and Equal Opportunities Monitoring Form to careers@icnarc.org. In your cover letter addressing how you meet the role requirements, please state whether you are applying for the permanent or maternity cover position or open to both.

Closing date: 1st July 2020 at noon

“We are committed to equality of opportunity for all staff and applications from individuals are encouraged regardless of age, disability, sex, gender reassignment, sexual orientation, pregnancy and maternity, race, religion or belief and marriage and civil partnerships.”